Great balls of fire

What is the meaning of "great balls of fire" when we use it for human?

I'm not sure about "when we use it for human." But anyone who reads the comic pages of newspapers (or the funny papers) probably recognizes "Great balls of fire" as a favorite interjection of Snuffy Smith, a friend of Barney Google's. The two were hill-billy goofballs ever since 1934, and very popular for a long period of time. What does it mean? Nothing much other than "Wow!" or "Holy Smoke!" Might come from the Bible, but probably not. SS, ESL

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