Unwired

Can "unwired" be said to mean "crazy", "deranged" or the like? What else can it mean when used to define a kind of person? Context is this:
"I speak for the lost, the loners, the deranged, the unwired.."
Thank you all.

It's not a common usage; it's a creative way to use the metaphor of "unconnectedness" and "lack of attachment" to describe the personality of the loose loner.